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The Horvath Lab

decoding mitochondrial genetics to transform treatments for neurological diseases

About Our Lab

The Horvath Laboratory is a research group dedicated to improving the understanding of genetic neurological conditions, with a focus on mitochondrial and neurogenetic disease. The focus of this research is to identify key molecular disease mechanisms with the aim of developing treatments for patients with rare inherited neurological conditions, such as mitochondrial and Charcot–Marie–Tooth diseases.

Principal Investigator

Rita Horvat

Rita Horvath, MD, PhD

Rita Horvath, Clinical Director of Research at Addenbrooke’s Hospital, Cambridge, has spent over 25 years developing using genomics and biochemistry to diagnose rare, inherited neurological disorders. She has had significant translational impact throughout this time, enabling genetic counselling and prevention through precision genetic approaches. She has established extensive international collaborations, having impact in low to middle income countries, showing her clinical and genetic expertise is having impact way beyond patients in the NHS. She has developed two clinical services which span inherited neurological disorders, with a particular interest in mitochondrial disorders, ataxia and inherited neuropathies. Her commitment to developing new treatments in rare diseases is unwavering, most recently through new gene therapy approaches that she has established in Cambridge.

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Postdoctoral Researchers

PhD Students

MPhil Students

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Contact us

Rita Horvath, Director of Clinical Research

John Van Geest Cambridge Centre for Brain Repair The ED Adrian Building Forvie Site

Robinson Way, Cambridge CB2 0PY

Department of Clinical Neurosciences, University of Cambridge

Email to connect

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